The intricate links between human and Earth systems are being increasingly represented in coupled human-Earth system models. These models can be used to explore the two-way feedback between the human and Earth systems due to changes in land productivity, water availability, extreme climatic events, land use/land cover, and greenhouse gas emissions. DOE’s state-of-the-science Energy Exascale Earth System Model (E3SM) has been coupled with the Global Change Assessment Model (GCAM): terrestrial productivity is passed from E3SM to GCAM, which then projects land use/land cover change and CO₂ emissions every five years and passes these outputs to the E3SM land and atmosphere components. We use the coupled E3SM-GCAM model to study the impact of land use/land cover change and CO₂ emissions on the carbon cycle and the feedback between the human and Earth systems. In the future, the study will be expanded to include potential decarbonization scenarios (such as meeting net zero CO₂ emissions targets) to quantify the impact of decarbonization pathways on biogeochemical cycles and feedback to the Earth system.