Land use in the United States (US) is driven by multiple forces operating at the global level, such as income and population growth, yield and productivity improvement, trade policy, climate change, and changing diets. Future land use has implications for biodiversity, run-off, carbon storage, ecosystem values, agriculture, and the broader economy. We investigate those forces and their implications from a multisector, multisystem dynamics (MSD) perspective focused on understanding dynamics and resilience in complex interdependent systems. Historical trends show slight increases in grassland and natural forest areas and decreases in cropland. We project these trends to intensify under higher pressures for agriculture land and reduce under lower pressures, with no evidence of tipping points toward larger agricultural land abandonment or deforestation. However, US sectoral output and trade, fertilizer use, N₂O and CH₄ emissions from agriculture activities, and CO₂ emissions from land use changes are substantially impacted under land use forcing scenarios.